İn Ottaman-Turkish medicine, there were some medical and surgical manuscripts which are known as "Hulasa" (summary). One of them was vvritten by "Physician Hayrettin." There is no biographic knowledge about the author, though it is estimated that he would live in 15th century. A copy of this manuscript is in the Library of Medical History Departm ent of Ankara University's Medical School. In this article, this m anuscript is analysed. According to a back-note, the book was copying by Ebubekr Sofyavi in 1677. The manuscript has four chapters. The fırst of them is related with "tibb-i nebevi" (prophet's medicine). Here, especially the saigns of prophet Muhammed related vvith cleanliness and dietary measures, showing the vvays of being healthy and protecting the health are covered in this chapter. The second chapter contains fifteen sections devoted to aııatomy and physiology. These sections cover some topics such as muscles, veins, stomach and intestines, kidney and bladder... The theory of medicine is the subject of the third chapter. The signs of recovery and poor prognosis, the methods of blodd letting... ete. are in the fifteen sections of this chapter.The last chapter vvhich contains 46 sections is the longest one of the manuscript Some topics covered by this sections are the kinds of psychiatric dieases, paralysis, penoumonia, jaundice.... As it is common nearly for ali manuscripts of the time, the humoral pathology hypothesis has an im portant role and a Central position in explanaüon and treatment of the diseases.